What minor issues I did have with the game were mostly of a technical nature - the game engine had erratic and unsmooth mouse movement in full-screen, so I switched to windowed mode after the first chapter. I got used to it, but I'd rather have played in full-screen to better admire the art. The very last section of the game had a couple of minor item/inventory related bugs, and one puzzle that I had to Google because I missed a visual cue. The puzzle itself was fine, but just a slight clue of where to look would have helped. None of this was game breaking though (and to be honest I usually accept that I'm probably going to end up looking up at least one or two puzzles in these kinds of games - I usually find that I had the right general idea but not precisely right execution, or it's a case of missing a small item somewhere).
Technobabylon was a game that made me want to imagine more, and for that reason alone I think it'll stay a favourite of mine for some time.